Name Of Drug Dosage Drug Class Indication Contraindication Adverse Effect Nursing

Responsibilities
Generic : 40 mg/ tab 1 Antihyperlipidemic  To reduce the risk  Contraindicated in Nausea & vomiting,  Monitor patient’s
Atorvastatin tab OD @ HS of MI, stroke, patients diarrhea, abdominal lipid and liver
Calcium angina, and hypertensive to the pain, constipation, function levels at
revascularization drug and in those dyspepsia & baseline and
Trade name: procedures in with active liver flatulence. periodically
Lipitor/ patients with no disease or Headache, skin thereafter.
Simvastatin evidence of CAD conditions linked rashes, dizziness,  Monitor patient for
with multiple risk with unexplained blurred vision, signs of
factors. persistent increases insomnia, dysgeusia. rhabdomyolyis,
 Heterozygous in transaminase Cholestatic jaundice, especially if taking
familial levels. pruritus, more than one class
hypercholesterole  Adolescent girl hypoglycemia, of lipid lowering
mia. must be at least 1 hyperglycemia. drugs.
 Adjunct to diet to year post- Anorexia,  Asses patient’s and
reduce elevated menarche pancreatitis, family’s knowledge
LDL, total alopecia, weight of drug therapy.
cholesterol, apo B, gain, Stevens-
and triglyceride Johnson syndrome.
levels to increase Back & chest pain,
HDL level in muscle cramps,
patients with peripheral edema,
primary malaise & fatigue
hypercholesterole Drug and food
mia and mixed interaction:
dyslipidemia. Cyclosporine, fibric
acid derivatives,
erythromycin, niacin,
azole antifungals.
Oral antacid
containing Mg & Al
hydroxide, colestipol,
efavirenz & rifampin.
Digoxin. Protease
inhibitors, diltiazem
HCl & grapefruit
juice. Norethindrone
 & ethinylestradiol.

Generic: 5 mg/ tab 1 tab Antihypertensive  Treatment of  Contraindicated  CNS: Headache, Assessment
Enalapril Maleate OD ACE inhibitor hypertension with allergy to dizziness,  History: Allergy to
alone or in enalapril. fatigue, enalapril, impaired
combination  Use cautiously insomnia, renal function, salt
with other with impaired paresthesias or volume
Trade name: antihypertensive renal function; salt  CV: Syncope, depletion,
Buergli s, especially or volume chest pain, lactation,
thiazide-type depletion palpitations, pregnancy
diuretics (hypotension may hypotension in  Physical: Skin
 Treatment of occur); lactation, salt- or volume- color, lesions,
acute and pregnancy. depleted turgor; T;
chronic CHF patients orientation,
 Treatment of  GI: Gastric reflexes, affect,
asymptomatic irritation, peripheral
left ventricular nausea, sensation; P, BP,
dysfunction vomiting, peripheral
(LVD) diarrhea, perfusion; mucous
 Unlabeled use: abdominal pain, membranes,
Diabetic dyspepsia, bowel sounds,
nephropathy elevated liver liver evaluation;
enzymes urinalysis, renal
 GU: Proteinuria, and liver function
renal tests, CBC, and
insufficiency, differential
renal failure,
polyuria, Interventions
oliguria, urinary  Alert surgeon, and
frequency, mark patient's
impotence chart with notice
 Hematologic: that enalapril is
Decreased being taken; the
hematocrit and angiotensin II
hemoglobin formation
 Other: Cough, subsequent to
muscle cramps, compensatory
hyperhidrosis renin release
 during surgery will
Interactions be blocked;
Drug-drug hypotension may
 Decreased be reversed with
hypotensive volume expansion.
effect if  Monitor patients
taken on diuretic
concurrently therapy for
with excessive
indomethaci hypotension after
n, rifampin the first few doses
of enalapril.
 Monitor patient
closely in any
situation that may
lead to a drop in
BP secondary to
reduced fluid
volume (excessive
perspiration and
dehydration,
vomiting,
diarrhea) because
excessive
hypotension may
occur.
 Arrange for
reduced dosage in
patients with
impaired renal
function.
 Monitor patient
carefully because
peak effect may
not be seen for 4
hr. Do not
administer second
dose until BP has
 been checked.

Teaching points
 Do not stop taking
the medication
without consulting
your health care
provider.
 Be careful in any
situation that may
lead to a drop in
blood pressure
(diarrhea,
sweating,
vomiting,
dehydration).
 Avoid over-the-
counter
medications,
especially cough,
cold, and allergy
medications that
may interact with
this drug.
 These side effects
may occur: GI
upset, loss of
appetite, change
in taste perception
(will pass with
time); mouth sores
(use frequent
mouth care); rash;
fast heart rate;
dizziness, light-
headedness
(usually passes in a
few days; change
 position slowly,
limit activities to
those not
requiring alertness
and precision).
 Report mouth
sores; sore throat,
fever, chills;
swelling of the
hands, feet;
irregular
heartbeat, chest
pains; swelling of
the face, eyes, lips,
tongue, difficulty
breathing.

Generic: Antipyretic  Mild to  Allergy to  Acute aspirin Assessment

Aspirin Analgesic moderate pain salicylates or toxicity:  History: Allergy to
(nonopioid)  Fever NSAIDs (more Respiratory salicylates or
Anti-inflammatory  Inflammatory common with alkalosis, NSAIDs; allergy to
Antirheumatic conditions— nasal polyps, hyperpnea, tartrazine;
Antiplatelet rheumatic fever, asthma, chronic tachypnea, hemophilia,
Salicylate rheumatoid urticaria); allergy hemorrhage, bleeding ulcers,
NSAID arthritis, to tartrazine excitement, hemorrhagic
osteoarthritis (cross-sensitivity confusion, states, blood
Trade name:  Reduction of risk to aspirin is asterixis, coagulation
Tromcor of recurrent TIAs common); pulmonary defects,
or stroke in hemophilia, edema, seizures, hypoprothrombine
males with bleeding ulcers, tetany, mia, vitamin K
history of TIA hemorrhagic metabolic deficiency;
due to fibrin states, blood acidosis, fever, impaired hepatic
platelet emboli coagulation coma, CV function; impaired
 Reduction of risk defects, collapse, renal renal function;
of death or hypoprothrombin and respiratory chickenpox,
nonfatal MI in emia, vitamin K failure (dose influenza; children
patients with deficiency related 20–25 g with fever
history of (increased risk of in adults, 4 g in accompanied by
 infarction or bleeding) children) dehydration;
unstable angina  Use cautiously  Aspirin surgery scheduled
pectoris with impaired intolerance: within 1 wk;
 MI prophylaxis renal function; Exacerbation of pregnancy;
 Unlabeled use: chickenpox, bronchospasm, lactation
Prophylaxis influenza (risk of rhinitis (with  Physical: Skin
against cataract Reye's syndrome nasal polyps, color, lesions;
formation with in children and asthma, rhinitis) temperature;
long-term use teenagers);  GI: Nausea, eighth cranial
children with fever dyspepsia, nerve function,
accompanied by heartburn, orientation,
dehydration; epigastric reflexes, affect; P,
surgery scheduled discomfort, BP, perfusion; R,
within 1 wk; anorexia, adventitious
pregnancy hepatotoxicity sounds; liver
(maternal anemia,  Hematologic: evaluation, bowel
antepartal and Occult blood sounds; CBC,
postpartal loss, hemostatic clotting times,
hemorrhage, defects urinalysis, stool
prolonged  Hypersensitivity: guaiac, renal and
gestation, and Anaphylactoid liver function tests
prolonged labor reactions to
have been anaphylactic Interventions
reported; readily shock  Give drug with
crosses the  Salicylism: food or after
placenta; possibly Dizziness, meals if GI
teratogenic; tinnitus, upset occurs.
maternal ingestion difficulty  Give drug with
of aspirin during hearing, nausea, full glass of
late pregnancy has vomiting, water to
been associated diarrhea, mental reduce risk of
with the following confusion, tablet or
adverse fetal lassitude (dose capsule
effects: low birth related) lodging in the
weight, increased Interactions esophagus.
intracranial Drug-drug  Do not crush,
hemorrhage,  Increased risk of and ensure
stillbirths, bleeding with that patient
neonatal death); oral does not chew
lactation. anticoagulants, sustained-
heparin release
 Increased risk of preparations.
GI ulceration  Do not use
with steroids, aspirin that
phenylbutazone, has a strong
alcohol, NSAIDs vinegar-like
 Increased serum odor.
salicylate levels  Institute
due to emergency
decreased procedures if
salicylate overdose
excretion with occurs: gastric
urine acidifiers lavage,
(ammonium induction of
chloride, emesis,
ascorbic acid, activated
methionine) charcoal,
 Increased risk of supportive
salicylate toxicity therapy.
with carbonic
anhydrase Teaching points
inhibitors,  Take extra
furosemide precautions to
 Decreased keep this drug
serum salicylate out of the
levels with reach of
corticosteroids children; this
 Decreased drug can be
serum salicylate very
levels due to dangerous for
increased renal children.
excretion of  Use the drug
salicylates with only as
acetazolamide, suggested;
methazolamide, avoid
certain antacids, overdose.
 alkalinizers Avoid the use
 Decreased of other over-
absorption of the-counter
aspirin with drugs while
nonabsorbable taking this
antacids drug. Many of
 Increased these drugs
methotrexate contain
levels and aspirin, and
toxicity with serious
aspirin overdose can
 Increased effects occur.
of valproic acid  Take the drug
secondary to with food or
displacement after meals if
from plasma GI upset
protein sites occurs.
 Greater glucose  Do not cut,
lowering effect crush, or chew
of sulfonylureas, sustained-
insulin with large release
doses (> 2 g/day) products.
of aspirin  Over-the-
 Decreased counter
antihypertensive aspirins are
effect of equivalent.
captopril, beta- Price does not
adrenergic reflect
blockers with effectiveness.
salicylates;  These side
consider effects may
discontinuation occur:
of aspirin Nausea, GI
 Decreased upset,
uricosuric effect heartburn
of probenecid, (take drug
sulfinpyrazone with food);
 Possible easy bruising,
 decreased gum bleeding
diuretic effects (related to
of aspirin's
spironolactone, effects on
furosemide (in blood
patients with clotting).
compromised  Report ringing
renal function) in the ears;
 Unexpected dizziness,
hypotension confusion;
may occur with abdominal
nitroglycerin pain; rapid or
Drug-lab test difficult
 Decreased breathing;
serum nausea,
protein vomiting.
bound
iodine (PBI)
due to
competition
for binding
sites
 False-
negative
readings for
urine
glucose by
glucose
oxidase
method and
copper
reduction
method
with
moderate to
large doses
of aspirin
 Interference
 with urine 5-
HIAA
determinati
ons by
fluorescent
methods
but not by
nitrosonaph
thol
colorimetric
method
 Interference
with urinary
ketone
determinati
on by the
ferric
chloride
method
 Falsely
elevated
urine VMA
levels with
most tests;
a false
decrease in
VMA using
the Pisano
method

Name Of Dosage Drug Class Indication Contraindication Adverse Effect Nursing

Drug Responsibilities
Generic :

Trade name: