Pharmaceutical consulting REF:

Rr. ‘3 Deshmoret’, Pall. Atermon Albania, I_4A19 20101509_Histaminic

Tirana, Albania
+355 69 40 15 790 REPORT:
gentianbregu@yahoo.com DATAS FOR THE HISTAMINIC CLASS IN PHARMACEUTICAL INDUSTRY, IN ALBANIA

Paxidorm tablets Coated tablets 25 mg x 20 Norma Chemicals Ltd_United Kingdom

Gravol Suppositories 25mg Suppositories 25 mg x 10 Church & Dwight Canada Corp (Mississagua)_Canada
Calmaben Sugar coated tablets 50 mg x 30 Pharmazeutische Fabrik Montavit GmbH-Austria
Drimen Tablets 50 mg x 100 Coup SA_Greece
R06AA Aminoalkyl ethers R06AA02 Diphenhydramine hydrochloride
Lomarin Tablets 50 mg x 10 Gemoynat Spa-Italy
Paxidorm syrup Oral solution 10 mg / 5 ml 150 ml x1 Norma Chemicals Ltd_United Kingdom
Gravol Liquid Oral solution 15 mg/ 5 ml 75 ml x1 Church & Dwight Canada Corp (Mississagua)_Canada
Histergran Cream 2% 25 g x1 Norma Chemicals Ltd_United Kingdom
Dermodrin Unguentum 20 mg / g 20 g x1 Pharmazeutische Fabrik Montavit GmbH-Austria

Istamex Tablets 4 mg x 20 ADELCO-Chromatourgia Athinon E. Colocotronis Bros. SA_G

R06AB02 Chlorpheniramine maleate
Istamex Syrup 2 mg / 5 ml 100 ml 1 ADELCO-Chromatourgia Athinon E. Colocotronis Bros. SA_G
R06AB Substituted alkylamines Fervex Enfants Granules for oral solution
(0.01 g + 0.28 g + 0.1g) x8 Upsa Conceil_France
R06AB05 Pheniramine Maleate + Paracetamol + Ascorbic Acid
Fervex Adults Granules for oral solution
(0.025 g + 0.5 g + 0.2 g x8 Upsa Conceil_France
Tetramil Eye drops solution (0.3 g + 0.05 g) / 10
100mlml x 1 Farmigea SPA_Italy

Prometazine 25mg Tablets 25 mg x 30 Profarma SH.A._Albania

R06AD02 Promethazine chlorhydratePrometazine 2% Cream 2.260 g / 100 g 30 g x1 Zeta Farmaceutici SPA_Italy
R06AD Phenothiazine derivatives Prometazine 2.5%-2ml Solution for injection 2.5% 2 ml x 10, x 100 Profarma SH.A._Albania

Primalan Scored tablets 10 mg x 14 Laboratoires Pierre Fabre Medicament_France

R06AD07 Mequitazine
Primalan Syrup 5 mg / 100 ml 60 ml x1 Laboratoires Pierre Fabre Medicament_France

Zyrtec Film coated tablets 10 mg 10 UCB Pharma AG_Switzerland

Histasin Tablets 10 mg 20 Actavis HF_Island
Rinalgit Divisible tablets 10 mg 20 ABC Farmaceutici Spa - Italia
CeHrizin Genericon Film coated tablets 10 mg 10 Genericon Pharma GmbH_Austria
R06AE07 Cetirizine hydrochloride
CeHrizin Hexal Bei Allergien Film coated tablets 10 mg 20 Hexal AG_Germany
R06AE Piperazine derivatives
CeHrizine Film coated tablets 10 mg 20 Profarma SH.A._Albania
Zyrtec Oral drops solution 10 mg/ml 10 ml 1 UCB Pharma AG_Switzerland
Rinalgit Oral drops solution 10 mg/ml 20 ml 1 ABC Farmaceutici Spa - Italia

Levocetirizine Zyxal Film coated tablets 5 mg 10 UCB Pharma AG_Switzerland

R06AE09 Dihydrochloride Zyxal Drop solution 5 mg / ml 20 ml 1 UCB Pharma AG_Switzerland

Rinasek Tablets Tablets 2.5 mg + 60 mg x 10 Hemofarm Koncern AD_Serbia

R06AX07 Triprolidine Hcl + Pseudoephedrine Hcl
Rinasek Syrup Syrup Syr x (1,25 mg + 30
100mg
ml)/ 5x ml
1 Hemofarm Koncern AD_Serbia

R06 Antihistamines
Rinolan Tab Tablets 10 mg x 10, x 30 Pliva-Zagreb_Croatia
Lorytec 10mg Tablets 10 mg x 10 Aegis LTD_Cyprus
Loratadine Alkaloid 10mg Tablets 10 mg x 10 Alkaloid AD-Skopje_Macedonia
ClariHne Tablets 10 mg x 10, x 21 Schering - Plough Europe_Belgium
Loratadine Tablets 10 mg x 20 Pharmachemie B.V._Netherlands
Loraderm Tablets 10 mg x7 Dermapharm AG_Germany
Flonidan 10mg Tablets 10 mg x 10 LEK Pharmaceuticals DD_Slovenia
R06AX13 Loratadine
Loratadin Tablets 10 mg x 20 Replekpharm AD Skopje_Macedonia
Pressing 10mg Effervescent tablets 10 mg 10 g x 10 Hemofarm Koncern AD_Serbia
Rinolan Syr Syrup 5 mg / 5 ml 100 ml x1 1. Pliva-Zagreb_CroaHa2. Pliva Krakow_Poland
Loratadine Alkaloid Syrup 5 mg / 5 ml 120 ml x1 Alkaloid AD-Skopje_Macedonia
Flonidan Oral Suspension5Mg/5Ml Syrup 5 mg / 5 ml 120 ml x1 LEK Pharmaceuticals DD_Slovenia
ClariHne Syrup 5 mg / 5 ml 120 ml x1 Schering - Plough Europe_Belgium
Pressing 5mg/5ml Syrup 5 mg / 5 ml 120 ml x1 Hemofarm Koncern AD_Serbia

R06AX15 Mebhydrolin napadisilat Mebhidroline Tablets 50 mg x 30 Profarma SH.A._Albania

Other antihistamines for
R06AX
systemic use Denerel 1mg Tablets 1 mg x 30, x 100 Medochemie Ltd_Cyprus
Zaditen Tablets 1 mg x 30 Novartis Pharma Switzerland AG_Switzerland
Frenasma Tablets 1 mg x 30 Faran SA_Greece
Ketofex Capseln Hard capsules 1 mg x 20 Dermapharm AG_Germany
Sosefen Syrup 2 mg / ml 20 ml x1 SO. SE. Pharm S.R.L._Italy
Zaditen Syrup 1 mg / 5 ml 100 ml x1 Novartis Pharma Switzerland AG_Switzerland
R06AX17 Ketotifen fumarate
Frenasma Syrup 1 mg / 5 ml 100, 125 ml
x1 Faran SA_Greece
Denerel Syrup Syrup 1 mg / 5 ml 100 ml x1 Medochemie Ltd_Cyprus
Ketofex Sirup Syrup 1 mg / 5 ml 100 ml x1 Dermapharm AG_Germany
Dovidin 0.025 % Eye drops solution 0.345 mg / 1 ml 5 ml x1 Anfarm Hellas SA_Greece
KetoKil 0.05 % Eye drops solution 0.069 g / 100 ml10 ml x1 Farmigea SPA_Italy
KetoKil 0.05 % Eye drops solution 0.069 g / 100 ml10 g x1 Farmigea SPA_Italy

Fexofenadine Telfast Film coated tablets 120 mg 10 Sanofi - Aventis Deutschland GmbH_Germany
R06AX26
hydrochloride Telfast Film coated tablets 180 mg 10 Sanofi - Aventis Deutschland GmbH_Germany
Aerius Film coated tablets 5 mg 10 Schering - Plough Europe_Belgium
Aerius Film coated tablets 5 mg 30 Schering - Plough Europe_Belgium
R06AX27 Desloratadine Aerius Oral solution 0.5 mg / ml 60 ml 1 SP Europe_Belgium
Aerius Oral solution 0.5 mg / ml 120 ml 1 SP Europe_Belgium
Aerius Oral solution 0.5 mg / ml 150 ml 1 SP Europe_Belgium
 cip 2010 cip 2009 cip 2008 Imports 2009, units Imports 2008, units Imports 2009, values Imports 2008, values Re-imbursement rate 2010 Re-imbursement rate 2009
Custom Pharmaceuticals Ltd_United Kingdom
USD 3.94 USD 2.92 USD 2.92 499 - USD 1,457 USD - - - - -
Church & Dwight Canada Corp (Montreal)_Canada
USD 3.40 USD 3.40 USD 3.20 5,040 4,680 USD 17,136 USD 14,976 - - - -
Pharmazeutische Fabrik Montavit GmbH-Austria
EUR 2.40 EUR 2.40 EUR 2.40 2,940 9,987 EUR 7,056 EUR 23,969 - - - -
Coup SA_Greece EUR 4.60 EUR - EUR - 10,000 - EUR - EUR - - - - -
Gemoynat Spa-Italy EUR 1.52 EUR 1.52 EUR 1.52 23,231 17,952 EUR 35,311 EUR 27,287 - - - -
Thorpe laboratories Ltd_United Kingdom
USD 6.86 USD 5.08 USD 5.08 - 1,000 USD - USD 5,080 - - - -
Church & Dwight Canada Corp (Montreal)_Canada
USD 2.80 USD 2.80 USD 2.60 3,600 3,960 USD 10,080 USD 10,296 - - - -
Pharmasol Ltd_United Kingdom / Apl: Wallace
USD Manufacturing
5.55 USD Chemists
- Ltd_United
USD Kingdom
- 5,400 2,184 USD - USD - - - - -
Pharmazeutische Fabrik Montavit GmbH-Austria
EUR 1.60 EUR 1.60 EUR 1.60 6,980 9,044 EUR 11,168 EUR 14,470 - - - -
EUR 74,567 EUR 87,990
ADELCO-Chromatourgia Athinon E. Colocotronis
EUR Bros.
0.60 SA_Greece
EUR - EUR - - - EUR - EUR - - - - -
ADELCO-Chromatourgia Athinon E. Colocotronis
EUR Bros.
1.40 SA_Greece
EUR 1.36 EUR - 3,000 - EUR 4,080 EUR - - - - -

Bristol Mayers Squibb_France EUR 1.69 EUR 1.69 EUR 1.69 9,000 15,000 EUR 15,210 EUR 25,350 - - - -
Bristol Mayers Squibb_France EUR 2.10 EUR 2.10 EUR 2.10 399,988 214,946 EUR 839,975 EUR 451,387 - - - -
Farmigea SPA_Italy EUR 2.59 EUR 2.77 EUR 2.75 - 6,720 EUR - EUR 18,480 - - - -
EUR 859,265 EUR 495,217

Profarma SH.A._Albania 147.00Lek 54.00Lek 54.00Lek 265 26,750 14,310Lek 1,444,500Lek 7.10 3.50 49% 2.60
Zeta Farmaceutici SPA_Italy EUR 1.42 EUR 1.52 EUR 1.51 21,540 13,544 EUR 32,741 EUR 20,451 - - - -
Profarma SH.A._Albania 300.00Lek 250.00Lek 210.00Lek 2,662 9,800 665,500Lek 2,058,000Lek - - - -

Laboratoires Pierre Fabre Production_France

EUR 2.19 EUR 2.19 EUR 2.19 6,000 5,998 EUR 13,140 EUR 13,136 - - - -
Laboratoires Pierre Fabre Production_France
EUR 1.66 EUR 1.66 EUR 1.66 6,270 6,585 EUR 10,408 EUR 10,931 - - - -
EUR 61,811 EUR 72,966

UCB Farchim AG_Switzerland EUR 3.50 EUR 3.50 EUR - 14,600 6,080 EUR 51,100 EUR - 67.50 7.20 11% -
ACTAVIS HF - IRLANDE, ACTAVIS UK LTD.EUR 1.25 EUR 2.50 EUR 2.50 26,500 28,843 EUR 66,250 EUR 72,108 24.10 7.20 30% 22.30
ABC FARMACEUTICI S.P.A.-ITALI EUR 2.60 EUR - EUR - - - EUR - EUR - 25.10 7.20 29% -
Genericon Pharma Ges.M.B.H. -Austri;EUR
Ge PharmaceuHcals
1.15 EURLtd - Bullgari
- EUR - 1,000 - EUR - EUR - 22.20 7.20 32% -
Salutas Pharma GmbH_Germany EUR - EUR - EUR - - - EUR - EUR - 22.90 7.20 31% -
Profarma SH.A._Albania 200.00Lek 200.00Lek - Lek 35,500 - 7,100,000Lek - Lek 14.40 7.20 50% 14.40
UCB Pharma SPA_Italy EUR 4.00 EUR 4.00 EUR - 4,824 4,040 EUR 19,296 EUR - - - - -
ABC FARMACEUTICI S.P.A.-ITALI EUR 3.10 EUR - EUR - - - EUR - EUR - - - - -

1. UCB Pharma AG_Switzerland 2. UCB EUR

S.A._Belgium
4.50 EUR 4.50 EUR - 28,660 16,210 EUR 128,970 EUR - - - - -
UCB Pharma SPA_Italy EUR 8.00 EUR 8.00 EUR - 3,408 1,408 EUR 27,264 EUR - - - - -
EUR 297,690 EUR 72,108
Hemofarm Koncern AD_Serbia EUR 2.40 EUR 1.70 EUR 1.70 - 3,210 EUR - EUR 5,457 - - - -
Hemofarm Koncern AD_Serbia EUR 1.70 EUR 2.40 EUR 2.40 - 2,481 EUR - EUR 5,954 - - - -
EUR - EUR 11,411

Pliva-Zagreb_Croatia EUR 0.98 EUR 0.98 EUR 1.06 4,676 - EUR 4,582 EUR - 18.80 6.70 36% 17.40
Aegis LTD_Cyprus EUR 1.10 EUR 1.05 EUR 1.66 - - EUR - EUR - 21.20 6.70 32% 18.70
Alkaloid AD-Skopje_Macedonia EUR 1.00 EUR 1.00 EUR 1.00 5,210 3,120 EUR 5,210 EUR 3,120 19.30 6.70 35% 17.80
Schering - Plough Europe_Belgium EUR 2.58 EUR 2.58 EUR 2.58 1,000 600 EUR 2,580 EUR 1,548 47.00 6.70 14% 45.90
PHARMACHEMIE B.V. - HOLLANDE; TEVA
EUR
PHARMACEUTICAL
- EUR WORKS
3.00
PRIVATE
EUR LIMITED- COMPANY - HUNGARI; CARDINAL
- HEALTH GERMANY- 405 GMBH
EUR GJERMANI; DISPHAR
- SUPPLY
EUR B.V. - HOLLANDE- - - - -
Mibe GmbH Arzneimittel_Germany EUR 0.63 EUR - EUR - - - EUR - EUR - 17.30 6.70 39% -
LEK Pharmaceuticals DD_Slovenia EUR 1.44 EUR 1.40 EUR 1.40 85,500 81,127 EUR 119,700 EUR 113,578 27.80 6.70 24% 24.90
Replekpharm AD Skopje_Macedonia EUR 1.40 EUR 1.15 EUR - 6,125 - EUR 7,044 EUR - 13.50 6.70 50% 10.20
Hemofarm Koncern AD_Serbia EUR 2.25 EUR 1.75 EUR 1.66 3,280 - EUR 5,740 EUR - 420.20 181.20 43% 31.20
Pliva-Zagreb_Croatia EUR 1.85 EUR 1.85 EUR 1.96 - - EUR - EUR - - - - -
Alkaloid AD-Skopje_Macedonia EUR 1.88 EUR 1.88 EUR 1.88 1,999 225 EUR 3,758 EUR 423 362.30 181.20 50% 334.70
LEK Pharmaceuticals DD_Slovenia EUR 2.57 EUR 2.57 EUR 2.57 15,855 18,445 EUR 40,747 EUR 47,404 495.30 181.20 37% 457.50
Schering - Plough Europe_Belgium EUR 3.00 EUR 3.00 EUR 3.00 - - EUR - EUR - 578.20 181.20 31% 534.00
Hemofarm Koncern AD_Serbia EUR 2.18 EUR 2.18 EUR 2.18 525 - EUR 1,145 EUR - 420.20 181.20 43% 388.10
EUR 190,506 EUR 188,895

Profarma SH.A._Albania 229.20Lek 229.20Lek 229.20Lek 110,900 333,400 25,418,280Lek EUR 76,415,280 - - - -
EUR 206,451 EUR 620,657

Medochemie Ltd_Cyprus EUR 1.78 EUR 1.78 EUR 1.47 84,173 29,447 EUR 149,829 EUR 43,287 3.40 1.70 50% 3.20
NOVARTIS PHARMA AG - ZVICER;NOVARTIS
EUR PHARMACEUTICALS
4.67 EUR UK4.67
LTD - EUR
ANGLI (APLIKANT
4.67 PER CERTIFIKATE:15,500
NOVARTIS PHARMA AG - 17,900
ZVICER) EUR 72,385 EUR 83,593 30.00 1.70 6% 27.70
Famar SA_Greece EUR - EUR 1.25 EUR 1.25 - 4,911 EUR - EUR 6,139 15.80 1.70 11% 7.40
Mibe GmbH Arzneimittel_Germany EUR 1.20 EUR - EUR - - - EUR - EUR - 11.60 1.70 15% -
Special product's line SPA_Italy EUR 3.82 EUR 4.50 EUR 4.48 9,632 7,680 EUR 43,344 EUR 34,406 - - - -
NOVARTIS PHARMA AG - ZVICER;NOVARTIS
EUR PHARMACEUTICALS
3.87 EUR UK3.87
LTD - EUR
ANGLI (APLIKANT
3.87 PER CERTIFIKATE:25,800
NOVARTIS PHARMA AG - 26,365
ZVICER) EUR 99,846 EUR 102,033 745.90 115.60 15% 688.90
Famar SA_Greece EUR 1.79 EUR - EUR 1.30 8,960 38,585 EUR - EUR 50,161 345.00 115.60 34% -
Medochemie Ltd_Cyprus EUR 1.30 EUR 1.30 EUR 1.65 5,000 5,000 EUR 6,500 EUR 8,250 250.60 115.60 46% 231.40
Mibe GmbH Arzneimittel_Germany EUR 1.20 EUR - EUR - 2,985 - EUR - EUR - 231.30 115.60 50% -
Anfarm Hellas SA_Greece EUR 4.00 EUR 4.00 EUR 4.00 - - EUR - EUR - - - - -
Farmigea SPA_Italy EUR 2.91 EUR 3.80 EUR 3.79 4,760 3,080 EUR 18,088 EUR 11,673 - - - -
Farmigea SPA_Italy EUR 2.91 EUR 2.80 EUR 3.79 1,000 200 EUR 2,800 EUR 758 - - - -
EUR 392,792 EUR 340,299

SANOFI-AVENTIS LLC - SHBA, SANOFI- SYNTHELABO

EUR 2.81LTD.EUR
- MBRETERI
2.81E BASHKUAR
EUR 2.81 2,000 2,000 EUR 5,620 EUR 5,620 - - - -
AVENTIS PHARMACEUTICALS INC. - SHBA,
EURSANOFI-SYNTHELABO
4.24 EUR LTD.
4.24
- MBRETERI
EUR E BASHKUAR
4.24 7,200 4,600 EUR 30,528 EUR 19,504 - - - -
1. Schering-Plough Labo N.V.Belgium2. EUR
Schering-Plough
4.52 S.P.A._Italy
EUR 4.52 EUR 4.52 - - EUR - EUR - - - - -
1. Schering-Plough Labo N.V.Belgium2. EUR
Schering-Plough
13.57 S.P.A._Italy
EUR 13.57 EUR 13.57 2,300 1,750 EUR 31,211 EUR 23,748 - - - -
1. SP Labo N.V. - Belgium2. Schering- Plough
EUR S.A. -3.84
FranceEUR 2.71 EUR 3.84 - - EUR - EUR - - - - -
1. SP Labo N.V. - Belgium2. Schering- Plough
EUR S.A. -7.69
FranceEUR 5.42 EUR 7.69 - - EUR - EUR - - - - -
1. SP Labo N.V. - Belgium EUR 9.60 EUR 9.60 EUR 9.60 1,700 700 EUR 16,320 EUR 6,720 - - - -
2. Schering- Plough S.A. - France EUR 83,679 EUR 55,592

EUR 2,166,761 EUR 1,933,723

Re-imbursement rate 2009 Re-imbursement rate 2008 Re-imbursement 2009 Re-imbursement 2008
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1.30 50% 2.60 1.30 50% 26,038 62,436Lek 39,065.00 92,309Lek

- - - - - - - Lek - - Lek
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- - - - - - - Lek - - Lek
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62,436Lek 92,309Lek

- - - - - - - Lek - - Lek
7.20 32% 22.20 7.20 32% 15,072 200,261Lek 23,079.00 326,307Lek
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7.20 50% - - - - - Lek - - Lek
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- - - - - - - Lek - - Lek
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200,261Lek 326,307Lek
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- Lek - Lek

5.10 29% 18.30 8.90 49% 10,155 98,577Lek 46,132.00 736,002Lek

5.10 27% 17.70 8.90 50% 620 6,528Lek 21,198.00 343,272Lek
5.10 29% 17.70 8.90 50% 5,839 58,185Lek 11,550.00 187,417Lek
5.10 11% - - - 275 5,508Lek 515.00 10,886Lek
- - 43.20 8.90 21% - - Lek - - Lek
- - - - - - - Lek - - Lek
5.10 20% 24.80 8.90 36% 55,470 527,732Lek 91,680.00 1,443,613Lek
5.10 50% - - - - - Lek - - Lek
5.10 16% 29.40 8.90 30% 740 9,633Lek 1,135.00 22,579Lek
- - - - - - - Lek - - Lek
167.30 50% 333.20 166.60 50% 87 18,826Lek 92.00 19,078Lek
167.30 37% 455.50 166.60 37% 445 86,799Lek 817.00 162,157Lek
167.30 31% 531.70 166.60 31% - - Lek - - Lek
167.30 43% 386.30 166.60 43% 7 1,499Lek 126.00 28,105Lek
813,287Lek 2,953,108Lek

- - - - - - - Lek - - Lek
- Lek - Lek

1.60 50% 2.60 1.30 50% 161,207 453,068Lek 258,452.00 545,717Lek

1.60 6% 27.60 1.30 5% 11,916 66,274Lek 12,890.00 62,944Lek
1.60 22% 7.40 1.30 18% 4,319 10,419Lek 10,500.00 17,963Lek
- - - - - - - Lek - - Lek
- - - - - - - Lek - - Lek
115.70 17% 685.80 115.20 17% 639 96,841Lek
- - 230.40 115.20 50% - - Lek - - Lek
115.70 50% 292.40 115.20 39% 560 90,362Lek
- - - - - - - Lek - - Lek
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716,964Lek 626,625Lek

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