DRUG STUDY

Prescribed and
Recommended
Generic Name
Dosage, Mechanism of Nursing
Brand Name Indication Contraindication Adverse Reaction
Frequency, and Action Responsiblities
Classifications
route of
Administration

Sodium ; tab OD, oral Restores buffering >cardiac arrest >Contraindicated CNS: tetany >Monitor pt closely
Bicarbonate capacity of the >metabolic to pts w/ metabolic for toxicity and
body and utilizes acidosis or respiratory CV: edema affectiveness
Arm & Hammer excess acid. >systemic or alkalosis & in those
Baking Soda, Neut, urinary with GI: gastric >Avoid using
Soda Mint alkalinization hypocalcaemia in distention, NaHCO3 and
>antacid w/c alkalosis may flatulence enteric-coated
Acidifiers and produce tetany, drugs together.
alkalinizing hypertension, Metabolic:
seizures or heart hypokalemia,
failure hyponatremia
>Also
contraindicated in
pts losing chlorides
bec. of vomiting or
continuous GI
suction & receiving
diuretics that
produce
hypochloremic
alkalosis
 DRUG STUDY

Prescribed and
Recommended
Generic Name
Dosage, Mechanism of Nursing
Brand Name Indication Contraindication Adverse Reaction
Frequency, and Action Responsiblities
Classifications
route of
Administration

Allopurinol 100mg OD, oral Reduces uric acid >Gout or >in patients CNS: fever, >Monitor uric acid
production by hyperurocemia hypersensitive to drowsiness, level to evaluate
inhibiting xanthine >Hyperuricemia drugs and in there headache, drugs effectiveness
Aloprim, Apo- oxidase caused by with idiopathic parenthesis, >Monitor fluid
Allopurinol + malignancies hemochromatosis peripheral intake & output,
Zyloprim >To prevent acute neuropathy, daily urine output
gout attacks neuritis of at least 2L and
Hyperuricemia and >To prevent uric CV: maintenance of
gout preparations acid nephropathy hypersensitivity neutral or slightly
during cancer EENT: epistaxis alkaline urine are
chemotherapy GI: desirable.
>Recurrent calcium nausea/vomiting, >Periodically
oxalate calculi diarrhea, monitor CBC &
abdominal pain, hepatic & renal
gastritis, dyspepsia function
GU: renal failure >Encourage pt to
Hema: anemia drink plenty of
Hepa: hepatitis fluids while taking
drug unless
otherwise
contrainidicated.
 DRUG STUDY

Prescribed and
Recommended
Generic Name
Dosage, Mechanism of Nursing
Brand Name Indication Contraindication Adverse Reaction
Frequency, and Action Responsiblities
Classifications
route of
Administration
> edema > Contraindicated
>hypertension to patients CNS: headache, >To enhance
Spironolactone > diuretic-induced hypersensitive to drowsiness, absorption, give
hypokalemia drug lethargy, confusion, drug with meals
Aldactone, > to detect >contraindicated in ataxia >Monitor
Norospiraton, hyperaldosteronis those with anuria, GI: diarrhea, gastric electrolyte levels,
Spiractin m acute or bleeding, fluid intake and
> to manage progressive renal ulceration, output, weight and
Potassium-sparing
primary insufficiency or cramping, vomiting BP
diuretic;
hyperaldosteronis hyperkalemia GU: inability to >protect drug from
antagonizes
m >use cautiously in maintain erection, light
aldosterone in the
50mg ;tab OD > heart failure, as pts with fluid or menstrual >inform laboratory
distal tubules,
adjunct to ACE electrolyte disturbances that pt is taking
increasing sodium
inhibitor, or loop imbalance, Skin: hirsutism spironolactone
and water
diuretic, with or impaired renal fxn because this may
excretion
without cardiac or hepatic dse interfere with tests
glycoside that measure
digoxin levels
 DRUG STUDY

Prescribed and
Recommended
Generic Name
Dosage, Mechanism of Nursing
Brand Name Indication Contraindication Adverse Reaction
Frequency, and Action Responsiblities
Classifications
route of
Administration

Omeprazole 40 mg IVTT q 12H Gastric acid-pump > short term > hypersensitivity CNS: headache, >Administer before
inhibitor: treatment for asthenia, vertigo, meals. Caution pt
Omepron suppresses gastric duodenal ulcer >use cautiously insomnia, anxiety, to swallow whole
Losec acid secretion by >treatment of with pregnancy and apathy not to open, chew,
specific inhibition heartburn or lactation Dermatologic: rash, or crush them
Antisecretory drug of the hydrogen- symptoms of inflammation, > administer
potassium ATPase GERD pruritus , dry skin antacids if needed
enzyme system at >short term GI: diarrhea, >advise pt to avoid
the secretory treatment of active abdominal pain, alcohol, products
surface of the benign gastric Respiratory: URI containing aspirin
gastric parietal ulcer symptoms, sough, or NSAIDs, and
cells; blocks final >GERD, severe epistaxis foods that may
step of acid erosive CV: Chest pain cause an increase
production esophagitis, poorly in GI irritation
responsive
symptomatic
GERD
 DRUG STUDY

Prescribed and
Recommended
Generic Name
Dosage, Mechanism of Nursing
Brand Name Indication Contraindication Adverse Reaction
Frequency, and Action Responsiblities
Classifications
route of
Administration

Omeprazole 40 mg IVTT q 12H Gastric acid-pump > short term > hypersensitivity CNS: headache, >Administer before
inhibitor: treatment for asthenia, vertigo, meals. Caution pt
Omepron suppresses gastric duodenal ulcer >use cautiously insomnia, anxiety, to swallow whole
Losec acid secretion by >treatment of with pregnancy and apathy not to open, chew,
specific inhibition heartburn or lactation Dermatologic: rash, or crush them
Antisecretory drug of the hydrogen- symptoms of inflammation, > administer
potassium ATPase GERD pruritus , dry skin antacids if needed
enzyme system at >short term GI: diarrhea, >advise pt to avoid
the secretory treatment of active abdominal pain, alcohol, products
surface of the benign gastric Respiratory: URI containing aspirin
gastric parietal ulcer symptoms, sough, or NSAIDs, and
cells; blocks final >GERD, severe epistaxis foods that may
step of acid erosive CV: Chest pain cause an increase
production esophagitis, poorly in GI irritation
responsive
symptomatic
GERD
 DRUG STUDY

Prescribed and
Recommended
Generic Name
Dosage, Mechanism of Nursing
Brand Name Indication Contraindication Adverse Reaction
Frequency, and Action Responsiblities
Classifications
route of
Administration

Ursodeoxycholic A naturally >Tx of selected pts >contraindicated CNS: headache, >Assses pt

acid 750 mg, 1 tab BID occurring bile acid with radiosolvent, with allergy to bile fatigue, anxiety, carefully for
that suppresses noncalcified salt, hepatic depression, sleep suitability of
Ursofalk, hepatic synthesis gallstones in impairment, disorder ursodiol therapy
URSO, of cholesterol and gallbladder for calcified stones,
URSO 250, inhibits intestinal whom elective radiopaque stones Dermatologic: >Give drug in two
Urso Forte absorption of surgery is or radiosolvent bile pruritus, rash, to three divided
cholesterol, contraindicated pigment, urticaria, dry skin, doses
Gallstone- leading to a >prevention of unremitting acute sweating, hair
solubilizing drug decrease gallstone formation cholecystitis, biliary thinning >Donot administer
cholesterol in obese pts obstruction, drug with
concentration in experiencing rapid gallstone GI: diarrhea, aluminum-based
the bile and a bile wt loss pancreatitis cramps, heartburn, antacids. If such
that is cholesterol >Tx of primary constipation, n/v, drugs are needed,
solubilizing and biliary cirrhosis anorexia, epigastric
not cholesterol (tablets only) distress >admin 2-3 hr after
precipitating. ursodiol
Respiratory: rhinitis,
cough >report gallstone
attacks (abdominal
pain, n/v),
yellowing of the
skin or eyes
 DRUG STUDY

Prescribed and
Recommended
Generic Name
Dosage, Mechanism of Nursing
Brand Name Indication Contraindication Adverse Reaction
Frequency, and Action Responsiblities
Classifications
route of
Administration

Itopride HCL GI symptoms of >increase in GI GIT: diarrhea, >do not administer

functional, non- motility abdominal pain with meals
Ganaton 50 mg film, DO ulcer dyspepsia
(chronic gastritis) >use precautiosly CV: headache >take before
Antiflatulence & i.e. feeling of in pregnancy and meals
anti-infammation, abdominal lactation, children
GIT regulators bloatedness, <16y/o, elderly
upper abdominal
pain, heartburn,
nausea and
vomiting
 DRUG STUDY

Prescribed and
Recommended
Generic Name
Dosage, Mechanism of Nursing
Brand Name Indication Contraindication Adverse Reaction
Frequency, and Action Responsiblities
Classifications
route of
Administration

Prevention & >hypercalcemia >hypercalcemia >swallow whole,

Ketosinel therapy of >disturbed amino do not chew/crush
1 tab TID damages d/t acid metabolism >administer w/
Fresenius Kabi faulty/deficient >use precautiously meals
(CromaMedic) protein metabolism in
in chronic renal hypophosphatemia
Ketoanaloznes & insufficiency > monitor serum Ca
essential amino level
acids