parameters resulting from physiological or biochemical processes in the body Laboratory testing for many of the chemical substances found in the body Importance of knowing the amount of various chemical substances in the body: 1. Helps the physician assess the function of certain organs 2. Helps the physician gain a better understanding of the patients overall health status Common Chemistry Panel Tests: 1. Blood Glucose (main source of energy of the body) a. Measures the amount of sugar called glucose in the blood b. Comes from carbohydrate foods c. Main source of energy used by the body d. Why it is done i. Check for diabetes ii. Monitor treatment of diabetes iii. Check for diabetes during pregnancy (gestational pregnancy) Different Types of Blood Glucose Tests: 1. Fasting Blood Sugar (FBS) a. Measures blood glucose after not eating for at least 8 hours b. Often the first done to check for prediabetes and diabetes 2. 2 Hour Postprandial Blood Sugar (PPBS) a. measures blood glucose exactly 2 hours after eating a meal b. screen patients for diabetes and to monitor insulin therapy of diabetic patients 3. Random blood Sugar (RBS) a. Measures blood glucose regardless of when you last ate b. Also called a casual blood glucose test 4. Oral Glucose Tolerance test a. Used to diagnose prediabetes and diabetes b. A series of blood glucose measurements taken after drinking a sweet liquid that contains glucose
c. Commonly used to diagnose diabetes that occurs
during pregnancy d. Not commonly used to diagnose diabetes in a person who is not pregnant i. Normal Value: 70 100 mg/dL (5.6 mmol/L) 5. Hemoglobin A1C test a. Preferred test for monitoring patients already known to have diabetes Test for Lipids and Lipoproteins 1. Cholesterol 2. Lipids ( free fatty acids ) 3. Lipoproteins (substances made up of lipids & proteins) Cholesterol Importance of Cholesterol: o Helps form bile acids that are produced in the liver and stored in the gallbladder o Vitamin D is formed from cholesterol at the skins surface during exposure to sunlight o Various hormones, such as cortisol, testosterone, and estrogen are synthesized from cholesterol. o High Cholesterol levels are strong indicators of those individual that are prone to coronary heart disease o The American Heart Association recommends that the cholesterol level in the blood less than 200 mg/dL. o Above 200 mg/DL is considered to be at an increased risk for developing atherosclerosis ( involves the buildup of fatty plaque on the interior lining of arteries, causing the arteries to narrow and harden. LDL o Bad cholesterol o High Levels of LDL The risk of heart disease increase o Normal Levels of LDL Less than 100 mg/dL Levels above 129 mg/dL borderline Above 159 mg/dL can be dangerously high High Density Lipoprotein (HDL) o Good Cholesterol o Normal Value Men: 40-50 mg/dL Female: 50 60 mg/dL
o Higher levels of HDL lower the incidence of heart
disease o Lower levels of HDL The great the patients risks for heart disease Triglycerides o Store energy o High Triglyceride levels Risk factor in heart disease o Normal Value Male: 40 160 mg/dL Female: 35 135 mg/dL
Blood Urea Nitrogen
o This test measures the amount of nitrogen in the blood that comes from the waste product UREA. o The test is done to: See if your kidneys are working normally See if your kidney disease is getting worse See if treatment of your kidney disease is working See if severe dehydration is present Normal Value 10 20 mg/dL o BUN is low during the 2nd or 3rd trimester of pregnancy