Non-contact Tissue Viability

Diagnostic Device
PROGRESS REPORT
GROUP 31
XINZI WANG
ZHIJIE QI
YOGA SHENTU
CLIENT: BRAD CLAY
PRESENTED BY: XINZI WANG

Overview
Project Scope
Specifications
Hardware - Alternative Designs
Hardware - Analysis
Chosen Design and Software
Next Steps

Scope
Noninvasive, handheld device to measure skin tissue

viability
Real-time feedback
Record, transmit data
Software interpret data and output result
Mockup and software will be delivered

Design Specifications
Design aspect

Specic requirement

Measurement depth

Up to 5 mm beneath the skin surface

Measurement accuracy

10% error

Opera;on temperature

15-30 C

Opera;on humidity

20-85%

Device Mass

500g

Target area per measurement

Handle within 5cm*3cm*7cm

Sensor within 8cm*5cm*5cm
5cm*5cm

Spa;al resolu;on

1 mm

Speed of acquisi;on

30 sec per measurement

Power Supply

USB

Device cost

$600

SoSware running ;me

Less than 1 min between data input and result output

Dimension

SoSware memory u;liza;on

SoSware developing cost

Installa;on: Less than 100 Megabyte

Database: less than 1 Megabyte / 100 pa;ents
$100

Design Specifications
Design aspect

Specic requirement

Measurement depth

Up to 5 mm beneath the skin surface

Measurement accuracy

10% error

Opera;on temperature

15-30 C

Opera;on humidity

20-85%

Device Mass

500g

Portability

Target area per measurement

Handle within 5cm*3cm*7cm

Sensor within 8cm*5cm*5cm
5cm*5cm

Spa;al resolu;on

1 mm

Speed of acquisi;on

30 sec per measurement

Power Supply

USB

Device cost

$600

SoSware running ;me

Less than 1 min between data input and result output

Dimension

SoSware memory u;liza;on

SoSware developing cost

Installa;on: Less than 100 Megabyte

Database: less than 1 Megabyte / 100 pa;ents
$100

Design Alternatives
HARDWARE
Discarded
Solutions

Blood Flow
Detector

Transcutaneous
Oximeter

Planar Optical
Oxygen Sensor

Infrared
Thermography
Camera

Hemoglobinbased Oximeter
(4 designs)

Discarded Solutions
Transepidermal Water Loss (TEWL)
Accuracy
Portability
Imaging of Radioisotopes
Exposure to radiation
Radioactive tracers
Magnetic Resonance (MR)
Portability
Cost

Blood Flow Detector

Laser Doppler Imaging Blood Flow
Low power laser source
Mirror system with step motors
Photo detector

Pros and Cons

High accuracy
u High resolution
u No contact with skin
u High cost
u Low portability
u Safety concerns
u

Transcutaneous Oximeter
Transcutaneous pO2 (tcpO2)
Electrodes
Electrolyte solution
Heating element

Pros and Cons

Requires contact with skin
u Elevated temperature skin burns
u

Planar Optical Oxygen Sensor

pO2
Optical sensor foil
Oxygen

sensitive dye
Reference dye

Handheld microscope
LED-based

excitation light

source
Optical filters
Color camera
u Sensor

can be shaped to
any desired geometry
u Requires contact with skin

Infrared Thermography Camera

Measures radiant heat emitted from skin
Infrared-sensitive camera
Compared to a blackbody source

Pros and Cons

Mature technology
u Heat Blood perfusion ?
u

Hemoglobin-based Oximeter
Reflection Method

Transmission Method
Scanner Type

Photo transistor

Camera Type

Hemoglobin-based Oximeter
Reflection Method

Transmission Method
Scanner Type
u Mainstream of the market in

u Measurement on limbs

point-oxygen-saturationmonitoring

receptors available at low cost

u Requires clamping the target

Camera Type
tissue

Hemoglobin-based Oximeter
Reflection Method

u
u
u

u
u

Transmission Method

Scanner
Type
Scanner Type
Fewer photo sensors lower cost
Minimizes interference
Motion of scanning complexity

Camera Type
Camera
Type
Quick and easy measurement
Ease of implementation

Analysis
Pugh Chart: Part I
Rela7ve
Importance

Blood Flow
Detector

Transcutaneous
Oximeter

Planar Op7cal
Oxygen Sensor

Infrared
Thermography
Camera

Accuracy

Cost

Resolu;on
Safety

Comfort

Ease of use

Maintenance

7
6
4
7
2

Portability

10

Speed of acquisi;on

Implementa;on
Reliability

WEIGHTED TOTAL

10
6

8
3
4
4
7
2
7
6
7

373

2
1
1
1
4
4
2
2
2

195

8
6
5
7
4
7
2
4
7

400

8
9
9
8
8
8
8
8
7

483

Analysis
Pugh Chart: Part II
Rela7ve
Importance

Reec7on
Oximeter
Scanner

Reec7on
Oximeter
Camera

Transmission
Oximeter
Scanner

Transmission
Oximeter
Camera

Accuracy

Resolu;on

Cost

Safety

Comfort

Ease of use

Maintenance

Portability

10

Implementa;on

10

Speed of acquisi;on

10

10

Reliability

505

541

385

409

WEIGHTED TOTAL

Chosen Design
Reflection Oximeter Camera
Software:
Programmed by Python
Data transfer method: USB cord
Data storage method: MySQL

Output: heat map

Schedule

Questions?