RTKs are essential for embryonic development. True
Activation loop in the TK domain leads to stimulation catalytic activity. True. Cytoplasmic portion of RTKs exhibits considerable diversity across the family, False. Es la extracelular.
Docking proteins involved in intracellular signal transduction True
SD2 domains bind to specific phosphotyrosines True SH3 domains bind to sequences in proline residues poor. False
Down regulation in RTKs causes a overexpression signaling