Myocardial Infarction, inadequate coronary blood flow rapidly results in myocardial

ischemia in the affected area. The location and extent of the infarct determine the effects on
cardiac function. Ischemia depresses cardiac function and triggers autonomic nervous
system responses that exacerbate the imbalance between myocardial oxygen supply and
demand. Persistent ischemia results in tissue necrosis and scar tissue formation, with
permanent loss of myocardial contractility in the affected area. Cardiogenic shock may
develop because of inadequate CO from decreased myocardial contractility and pumping
capacity.