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S C H O O L O F M E D I C I N E C O R E F A C I L I T I E S N E W S L E T T E R
V O L U M E 6
Spotlight On: The
Development Disabilities
Practice-Based Research
Network (PBRN)
A new kind of PBRN, facilitating the
evolution of primary care for all patients
Practice-Based Research
Networks (PBRNs) are
organizations of community
healthcare practices that
collaborate with academic and
community partners to improve
health care through translational
research, particularly primary
care delivered in community
practices. PBRNs were
developed to assure that
research leads to better health
outcomes because it is informed
by front-line community based
clinicians. In PBRNs, clinicians
are involved in the entire research process, including
determining the research agenda, framing and defining the
research questions, informing the design of the study,
participating in data collection, interpreting study results,
disseminating study findings, and incorporating new knowledge
into clinical practice.
The federal government regards persons with developmental
disabilities (DD) to be a "priority population" for research, and
many governmental agencies include them in their lists of
"medically underserved populations." Developmental disabilities
include a wide variety of chronic conditions that cause
significant lifelong physical or mental impairments. Examples
July 10, 2014
This newsletter is published
by the Office of Research
Administration here at the
Case Western Reserve
University School of Medicine.
To get in touch with the editor,
email somcores@case.edu.
2nd Annual SOM
Institutional
Scientific Core
Facility Retreat
The second annual retreat is
scheduled for August 25,
2014. Retreat participation is
by invitation only and is
primarily for Core Facility
Directors and Managers, as
well as Administrative/Clerical
Staff, however there will be
limited additional seating
available. If you'd like to be
invited to this years retreat,
please go here to request an
invitation. (register)
Link the Core
Facilities page to
your Core home
page
Keep our page at your
include
intellectual
disabilities of any
cause, cerebral
palsy, autism
spectrum
disorder, and
Down syndrome.
For the past 20 years, Dr. Carl Tyler MD, MSc, a practicing
physician at the Cleveland Clinic, has focused his work on
improving the health and health care of persons with DD through
clinical care, research, education, and training. After completing
a 3-year NIH-sponsored fellowship in Practice-Based Research
Design and Methodology at CWRU under mentors and PBRN
Shared Resource Directors James Werner PhD MSSA and Kurt
Stange MD PhD, Dr. Tyler received additional funding to create
a Development Disabilities Learning Collaborative with local
stakeholders. The success of the DD Learning Collaborative led
to the creation of the Developmental Disabilities (DD) PBRN.
The network is devoted to conducting translational research
with developmentally disabled patients and their health and
service providers.
The DD PBRN is the only PBRN in the country dedicated to
conducting translational research with DD patients and their
health and service providers. In addition to receiving
infrastructure support from the PBRN Shared Resource, this
new PBRN is supported by high levels of stakeholder
investment including the Arc of Greater Cleveland, United
Cerebral Palsy of Greater Cleveland, clinicians from local
hospital systems, residential care providers, as well as patients
with developmental disabilities and their family advocates. This
diverse group has excellent research potential and recently
submitted a proposal to the Patient Centered Outcomes
Research Institute for an investigation to be conducted within
the DD PBRN.
If you are interested in engaging the DD PBRN, please contact
the PBRN Shared Resource at pbrn@case.edu or 216-368-
4622, or visit their website,
http://corefacilities.case.edu/clinical.php#pbrn.
Rodent Behavioral Core
Re-Opens
Under new Director, Dr. Hiro Arakawa
The Rodent Behavioral Core facility at the School of Medicine is
happy to announce its grand re-opening! Under the leadership of
its new Director Hiro Arakawa, PhD, the Rodent Behavioral
Core provides in-depth characterization of rodent behavior with
state of the art testing equipment, methodology and expertise.
The Core offers a comprehensive battery of tests in mice which
fingertips! Add a link to the
Core Facilities home page
(http://corefacilities.case.edu/)
to your Core website. For
assistance, please contact
Anne DeChant:
akd6@case.edu, 216-368-
8867.
Cancer Stem Cell
Conference
Register today for the first
CWRU National Center for
Regenerative Medicine Cancer
Stem Cell Conference, which
will be held right here in
Cleveland from August 17-20,
2014. Visit their website here
for information about abstract
deadlines, accommodations
and registration.
About the Publication
To get in touch with the editor,
email somcores@case.edu.
include learning and
memory, place/fear
conditioning,
pain/analgesia, anxiety-
related, depression-
related behaviors, and
various social behaviors,
all with a high degree of
repeatability. Dr. Arakawa
and his team will assist in
all aspects of protocol
development, including
design, execution, and
data analysis. Finally, the
Rodent Behavioral Core
provides extensive
training and supervision in
conducting behavioral tests and will allow independent
unsupervised use of equipment after completion of training.
For more information on the Rodent Behavioral Core, including a
comprehensive list of all behavior tests, equipment, pricing, and
IACUC requirements, visit their website here.
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