2013 Project Lead The Way,

Inc.
PBS Project 6.1.1 Student Response Sheet Page 1

y

Project 6.1.1: Student Response
Sheet

Introduction
Anna Garcia was only 38 when she died, meaning that at least one of her body
systems was no longer able to support life. The failure of one or more of her body
systems may be the result of injury due to an accident or could be the result of an
illness or a combination of illnesses. Before we can determine which system or
systems failed or what caused the failure which led to her death, we have to learn
more about the human body.

The human body is an amazing machine composed of many interrelated systems
which are in turn composed of cells, tissues, and organs that act independently and
interdependently within the body. No individual component of a human body works
alone. Components of each system in the body affect or interact with every other
system. The body is dependent upon the many interactions between all systems and
structures to maintain homeostasis and health. In this activity you will investigate the
different body systems that make up the human body and explore all of the ways
Annas various illnesses affected each body system, potentially resulting in her
premature death.

Procedure:

1. Look back in your course file and list all of the ways each body system was
impacted by the illness or disease Anna Garcia experienced in her life.
2. Reference Autopsy Reports, Medical Histories and past lab activities to help you
organize this information.
3. Record any evidence that shows how the illness or disease may have been
involved with her untimely death.
4. Be specific about relationships between body systems and illness. You will use
this chart to help construct your final timeline that explains how Anna died.
5. You will need to eventually upload this document to your e-portfolio under Annas
Cause of Death.








2013 Project Lead The Way,

Inc.
PBS Project 6.1.1 Student Response Sheet Page 2




Part II: Annas Illnesses

Illnesses Effect on System (if applicable)

Diabetes Sickle Cell
Anemia
Heart
Disease
Urinary Tract
Infection
Cardiovascul
ar









Erode Blood Vessal
walls

Cause Disease

Neuropathy Loss of
senses in outer
extremeties



















Low WBC
count, RBC
do not flow
smoothly,
RBC sickle
shaped, Low
blood
amount to
extremities
Veins and
Arteries
harden, plaque
build up, clots
of blood
Sepsis, Sepsis
Shock, more
blood cells
taken to the area
Digestive









Gastroparesis-
stomach takes too
long to empty
contests because
Vagus nerve gets
damage.
Bilirubin gallstones
- sickle cells die in
20 days; liver
breaks down the
bilirubin; extra
bilirubin can
become a gallstone
in the gallbladder


(bilirubin forms bile)



Less blood
goes to the
digestive
system.
Intestinal
Ischemia
Flow of
oxygen rich
blood to
stomach is
blocked,
nutrients
cant be
absorbed
More Sepsis,
also UTI can
cause E Coli
which lives in
the digestive
system as well
2013 Project Lead The Way,

Inc.
PBS Project 6.1.1 Student Response Sheet Page 3



Immune









Immune System
destroys insulin
producing cells. People
more susceptible to
diseases.
http://www.diabeticconn
ect.com/diabetes-
videos/general/1977-
how-diabetes-affects-
immune-system
Low WBC leads to
weakened Immune
System. More
susceptible to infections
and diseases.
Autoimmune
system,
Immune system
attacks own
antigens.
Increased
production of
lymphocytes (B &
T cells) and
antibodies
against the
bacteria;
Inflammatory
response (may
increase
additional UTI
and/or damage to
urinary tract
structures.
SEPSIS!!!!!!!!!
Nervous









Neropapthy causes
nerves to tingle in
the extremities.
Lack of blood to
extremitites, tingly
feelings.




Blockages,
heart cant
pump,
nerves die.
Wacky
EKGs,
ZOMG
Spinal Cord
Abnormalites can
foster UTIs!!!!
Maybe some
Sepsis
Respiratory









Lung Damage and
then breathing
issues.
Ketoacidosis
Acute Chest
Syndrome,
breathing issues,
lack of blood to
organs
Breathing
Issues,
Acute Chest
issues
Sepsis Life
threatining,
extreme bacteria
levels, damage
multiple organ
systems
resulting in
death
Urinary









High Blood
Glucose-Bacteria
Growth
Kidney Stones and
Damage
SLenic
Sequestration
Urinary tension
after acute chest
syndrome.
Common Urinary
tract infection
Causes
damge to
organs like
kidneys,
which filters
urine
inefficiently
afterwards
Urinary tract
infection, Sepsis

Sources Used:
2013 Project Lead The Way,

Inc.
PBS Project 6.1.1 Student Response Sheet Page 4

http://www.ncbi.nlm.nih.gov/pubmed/7395009

https://scinfo.org/problem-oriented-clinical-guidelines/specific-problems-urinary-
tract-symptoms

http://www.mayoclinic.org/diseases-conditions/sepsis/basics/definition/con-
20031900

http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Urinary_tract_infe
ctions

http://www.heart.org/HEARTORG/Conditions/HeartFailure/WarningSignsforHeartF
ailure/Warning-Signs-of-Heart-Failure_UCM_002045_Article.jsp