1inevery691babiesintheUnitedStatesisbornwithDownSyndrome.PeoplwithDown Syndromearejustlikeyouandme,butinsomewaysaredifferent.(Unknown1,2014)Down Syndromeisagenticdisorder.TherearealotofdifferenttypesofDownsyndrome,atypethatis inherited,anditiscausedbyanextrachromosome. DownSyndromedevelopswhenthereisanextrachromosome.Thishappensdurningthe reproductiveprocess.Acellusuallydividesintotwogermcellseachcontaining22 chromosomes.Sometimesthatprocessdoeshappenproperly.Oneofthecellsmightcontain 22chromosomesandtheothermightcontain24chromosomes.(unknown1,2014)Thisiscalled nondisjunctionbecausethecellsdidn'tseparatecorrectly.25%ofthetimeitisthespermcells thatcarriestheextrachromosomeand75%ofthetimetheextrachromosomeisintheeggcell. Also,alotofpeoplewithDownSyndromehavetwonormalcopiesofchromosome21sbutthey alsohaveextramaterialofchromosomeattachedtoadifferentchromosome. (Unknown,2014)Thismakessomeonehavethreechromosome21swhichcausesDown Syndrome.(seegraph#2toseeotherreasonsDownsyndromecanhappen) DownSyndromeisagenticdisorderthatisinherited.

(Unknown2,2014)Ifyouareacarrierthere isandincreasedriskofyourchildhavingDownsyndromebutitisrare.Acarrierwillhave45 chromosomesinsteadof46chromosomes.(unknown2,2014)DownSyndromeisonlyinherited withtranslocationDownsyndrome.TransclotionDownsyndromeiswhenthereisextra chromosome21materialonadifferentchromosome.Thecarrierhasextramaterialbutonlyone chromosome21.Theywon'thaveanysymptomsofDownsyndrome. There'salotofdifferenttypesofDownsyndrome.Somedifferenttypesaretrisomy21, transclotion,andmosaicsim.Trisomy21iswhentheextrachromosome21comesfromthe spermoreggcell.SomeonewiththistypeofDownsyndromewillhave46chromosomesbut willhavegenticmaterialof47chromosomes.(Unknown,2014)Thistypeisvery common.Transclotioniswhenapieceofchromosome21isonchromosome14.Peoplewith transclotionwillhavethesamecharacteristicsassomeonewithtrisomy21buttheyhavethree copiesofchromosome21.Mosaicsimiswhensomeonehasamixofcellsandsomecontain46 chromosomesandotherscontain47chromosomes.Durningtheprocessofreproductionthe chromosome21didn'tsplitevenly,soonecellreceived47chromosomes. ThereisalotofdifferenttypesofDownsyndrome,atypethatisinherited,anditiscausedbyan extrachromosome.IfsomeoneyouknowhasDownsyndromejustremembertheyhavealotin commonwithusbutinsomewaystheyaredifferent.Theystillliketoplaygames,justlikeyou, andtheyliketowatchmoviesjustlikeyou.Inmostwaystheyarejustlikeyou. Sources: Source#1"DownSyndrome."GeneticsHomeReference.N.p.,n.d.Web.17Mar.2014. (Unknown,2014)

 Source#2."WhatIsDownSyndrome?"WhatIsDownSyndrome?N.p.,n.d.Web.19Mar. 2014.(Unknown1,2014) Source#3"FactsAboutDownSyndrome."NationalAssociationforDownSyndrome.N.p.,n.d. Web.23Mar.2014.(unknown2,2014)