It is much more important to know

what kind of patient has a disease, than to know what kind of disease a patient has
Caleb Parry. 18th Century physician, Bath.

We used to think our fate was in our stars. Now we know, in large measure, our fate is in our genes
J.D Watson. Time Magazine 20 March 1989

24 million ptes living with cancer 2010

24 million ptes living with cancer 2010

173

134

CA&C: 255,900 CASES

Country
GUATEMALA

Populacin (Thousand)

# New Cncer Cases

ASR (w)

Risk Cancer <75 years %

Number deaths (thousa)

5 year Prevalen Th/x100

Types of Cancer M: Pro,G, Liv, Lung, Leu F: Cacu, G, Liv, Br, CU M: Pro,G,Lung,Leu,Liv F:Cacu,Br,G,CU,Liv M: Pro, G, Li, Lung, Leu F: Cacu,S, Br,Liv,CU M:Pro,G,Liv,Leu,CR F:CaCu,Br,S,Liv,CR M:Pro,G,CR,Lung,Leu F:Br,CaCu,G,CR, Thy M: Pro,Lung,G,CR,NHL F:Br,CaCu,CR,G,Lung

13686 6133 7318 5667 4519 3398 40721

14.2 7.8 8.9 5.6 7.7 4.6 48.8

154.1 15.3 135.9 13.6 180.5 18.3 140.2 14.5 176.3 17.2 143.9 14.7 160.2 15.6

9.1 5.0 5.7 3.3 4.3 3.0 30.4

31.4/ 387.2 18/ 437 20/ 440 13.2/ 361.3 18.3/ 550.1 10.7/ 448.4
111.6/ 437

EL SALVADOR

HONDURAS

NICARAGUA

COSTA RICA

PANAMA

TOTAL

Pro: Prostate; G: Gastric; Leu: Leukaemias; Liv: Liver; Br: Breast; , CU: Corpus Uterine; CR Colom & Rectum, Th: Thyroid; NHL: Non Hod Lymphoma; CaCu Cervix Uterine

Country

Populacin (Thousand)

# New Cncer Cases

ASR (w)

Risk Ca <75a. %

No deaths (thou)

5 year Preva Th/x100

Types of Cancer

CUBA

11204 9952 2707 1333

31.5 13.1 5.1 2.1

193.0 151.7 187.8 153.4

19.4 16.1 20.0 16.1

21.2 8.0 3.2 1.4

71.9/ 783.4 31.6/ 466.2 12.4/ 653.7 5.3/ 499.0

M: Pro,Lung,CR,Lym, Bla F: Br,Lung,CR, Cacu,CU M:Pro,Lung,Li,CR, G F: Br, CaCu,CR, Lung, Li M: Pro,G,Lung,CR,Bla F: Br,CaCu,CR,G,CU M: Pro,Lung,CR,G,Pan F: Br,CR,CaCu,CU,Ov

DOMINICAN REPUBLIC

JAMAICA

TRINIDAD & TOBAGO

BARBADOS

255
337 25788

0.8
0.5 53.1

207.9
156.4 175.0

21.9
18.1 15.6

0.5
0.3 34.6

2.0/ 950.8
1.4/ 549.5 124.6 532.1

M: Pro,CR,G,Lung,Pan F: Br,CR,CaCu,CU,Ov
M. Pro,CR,Lung,G,Eso F: Br,CaCU,CR,CU,Ov

BAHAMAS

TOTAL

Pro: Prostate; G: Gastric; Leu: Leuk; Liv: Liver; Br: Breast; , CU: Corpus Uterine; CR Colom & Rectum, Th: Thyroid; NHL: Non Hod Lymph; CaCu Cervix Uterine,Ov:Ovary

Cancer epidemiology world wide

3TH INCIDENCE 1TH MORTALITY

16.5%

8.5%

LUNG

55% developing countries

LUNG CANCER IN MEXICO SAME DATA IN CENTRAL AMERICA AND CARIBBEAN ??

LUNG CANCER IN MEXICO SAME DATA IN CENTRAL AMERICA AND CARIBBEAN ??

LUNG CANCER IN MEXICO SAME DATA IN CENTRAL AMERICA AND CARIBBEAN ??

LUNG CANCER IN MEXICO SAME DATA IN CENTRAL AMERICA AND CARIBBEAN ??

LUNG CANCER IN LATIN AMERICA SAME DATA IN CENTRAL AMERICA AND CARIBBEAN ??

EGFR mutation

K RAS: 16.5% Tx TKI: Independently to all factors

LUNG CANCER IN MEXICO SAME DATA IN CENTRAL AMERICA AND CARIBBEAN ??

EGFR mutation

LUNG

thyroid transcription factor 1

COMPROBACION POR IHQ

EGFR MUTATION ANALYSYS CENTRAL & CARIBBEAN

RESPONSE TO TKI

PEMETREXED CETUXIMAB

CDDP TK

TAC

PET
11-1-2011 Guatemala Squamous Cel. Ca. 79 year old

Salud publica Mex ,Vol 53, supp 2, 2011

18.9%
88.5% 81.1% 11.4% 30.4% 69.5%

Salud publica Mex ,Vol 53, supp 2, 2011

(CONCLUSIONS)

Total Population: 66,506,000.00 millons .

CA: 160.2 Caribbean: 175

Cancer: Age Stand Rate (w)

High rate: Cuba, Bahamas, Jamaica Panam, Costa Rica

Lung Cancer Incidence:

CA: 5-6th Caribbean: 3-5th

High Incidence : Cuba, DR, Jamaica, T&T

TOTAL cases of Lung Cancer: 9125 TOTAL cases of Cancer: 101900 (11%)