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Problem Set 8
Announcements:
• Please email me if you have any suggestions for how to organize the final section.
• This problem set covers lecture 14 and 15.
1. What is the molecular mechanism by which Gleevec acts on treating Chronic Myelogenous
Leukemia? Why is this treatment usually done late in the leukemia's development?
5. How is Myc overexpressed in Burkitt's Lymphoma? What are the normal functions of Myc?
6. List two similarities and two differences between HNPCC and FAP.
8. Describe the pathway by which mitogens control the rate of cell division.
9. A patient comes into the hospital that is found to have B cell lymphoma. Would you suggest
traditional chemotherapy for this patient? Why or why not?