(0:41) Welcome
Welcome back! Stacy and Sarah are now recording the show bi-coastal
Stacy is in Seattle and well caffeinated for this week's recording
Matt and Stacy are on day 6 of their summer travel adventure
Matt left Virginia and drove across the country to meet Stacy in Seattle, visiting a number of National Monuments with Cole along the way
Finn and Stacy went to New York, and Wesley was with Stacy's mom
It was nice to all meetup and come together on the West coast
Sarah hopes the rest of the trip is smooth sailing and filled with memorable adventures

Sarah is still trying to settle into summer with her family
It was off to a hectic start, and the kids are starting to settle into free time
They are planning to have a low key summer this year
The family is working on the next level of their citizenship, so that will be taking up a bit of time

Sarah wanted to take this podcast to discuss the recent updates she made to the Autoimmune Protocol
She wants to use every channel she has to communicate this latest science
In the grand scheme of things, these are relatively small changes, but they are important tweaks

The Paleo Approach was published in January 2014, so in those 5 1/2 years there has been a lot of science published that is very relevant to understanding how diet and lifestyle impact immune function
Sarah has been procrastinating finishing The Gut Microbiome book
She is in this last hard grind of that project and is happy to get distracted by any other project right now

The research form the last three to five years has been where Sarah has spent most of her time, which will also feed into the Gut Microbiome book as well
Since last fall Sarah has been spending time doing a really thorough review of this literature
Looking for new studies that she may have missed
Doing targeted searches for specific topics
Working to understand what is preliminary research

These new revisions to the autoimmune protocol reflect the new science that adds to our understanding of these gray area foods and ultimately shifts that category a little bit



(11:15) The Latest Findings
There are now two clinical trials published using the AIP where the participants are given The Paleo Approach and The Autoimmune Wellness Handbook
They are taken through Angie's SAD to AIP in 6 transition program and then they maintain AIP strictly for another 4 to 5 weeks depending on the study
We are measuring improvements
The first study was published in fall 2017
It was done on patients with active inflammatory bowel disease
They transitioned to the autoimmune protocol and over those 6 weeks with what was called a 5-week maintenance phase
73% of the patients were in full clinical remission by 6 weeks
So by the time they finished transitioning to the AIP they were in full clinical remission
100% of participants saw improvements in those markers of disease activity and they still all saw continuous improvements in those markers throughout the five-week maintenance phase
So a really compelling study right out of the gate


Just published last month in 2019 there was a very similarly designed study on women with Hashimoto’s thyroiditis
They did the same gradual transition over 6-weeks, followed by a 4-week maintenance phase
This study was looking at a condition that is not as straightforward to measure how active the immune attack is
They were able to measure a very substantial decrease in the clinical symptom burden
The average at the beginning of the study was 92 points, and after four weeks on the full AIP was down to 29
Which is basically going from this is impacting my everyday life to this is a minor nuisance
This study again produced very compelling data



There is a study getting off the ground right now on the impact that AIP plays on Psoriasis and Eczema, and if you are interested and able to support this kind of research, please visit: https://www.indiegogo.com/projects/medical-study-on-eczema-psoriasis-and-aip#/
The more medical studies that w