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The $1,000 Genome: The Revolution in DNA Sequencing and the New Era of Personalized Medicine
The $1,000 Genome: The Revolution in DNA Sequencing and the New Era of Personalized Medicine
The $1,000 Genome: The Revolution in DNA Sequencing and the New Era of Personalized Medicine
Audiobook10 hours

The $1,000 Genome: The Revolution in DNA Sequencing and the New Era of Personalized Medicine

Written by Kevin Davies

Narrated by Johnny Heller

Rating: 3 out of 5 stars

3/5

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About this audiobook

Since the conclusion of the Human Genome Project in 2003, scientists have been racing toward a grand goal: offering individuals a decoding of their complete genetic makeup for just $1,000. As Kevin Davies reveals in this exquisitely reported account, the $1,000 genome will be a reality by 2011 and it will usher in a whole new era of personalized, genomic medicine. Capable of presenting much more advanced information than the current crop of cheek-swab services, the $1,000 complete genome raises some extraordinary possibilities. We will be able to learn if we have genes that predispose us to a host of diseases and to take a wide range of preventative measures. Drug companies may be able to create versions of drugs tailored specifically to our individual DNA. But we may also face the psychological burden of learning that we have the gene for an incurable disease, such as Parkinson's.

Acclaimed author Kevin Davies introduces the pioneers of this medical revolution and probes deeply into both the medical benefits and ethical issues of personal genetic testing, also exploring the psychological complexities of learning one's DNA results, based on both his own experience of being tested and that of a number of others. The $1,000 Genome is an indispensable guide to the new era of personalized medicine.
LanguageEnglish
Release dateSep 22, 2010
ISBN9781400188505
Author

Kevin Davies

Kevin Davies, Ph.D., is the author of The $1,000 Genome. His previous book Cracking the Genome was translated into 15 languages. He is currently Editor-in-Chief of Bio•IT World, a trade magazine covering the role of technology in the life sciences. He was the founding editor of Nature Genetics, the world's leading genetics journal, which he headed for its first five years. He has also written for the Times (London), Boston Globe, New England Journal of Medicine, and New Scientist, among others. His first book, Breakthrough (co-authored with Michael White) told the story of the race for the BRCA1 breast cancer gene. Davies holds an M.A. in biochemistry from the University of Oxford and a Ph.D in molecular genetics from the University of London. He held postdoctoral fellowships at MIT and Harvard Medical School before moving into science publishing as an editor with Nature magazine. He lives in Lexington, Massachusetts.

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Rating: 3 out of 5 stars
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  • Rating: 2 out of 5 stars
    2/5
    This book should be titled 'The new companies that want to sequence your genome', because unfortunately that's what it's mostly about. Davies touches on all of the interesting technologies, applications and possible consequences of this 'revolution' that is certainly going to occur, but doesn't try to get grips with any of them.Topics such as epigenetics and computational biology are mentioned and not explored, when they will both be key to genome sequencing fulfilling it's real potential, whereas the sequencing itself and principles involved are explained but probably not accessible enough for the non-biologist. Therefore there is little to recommend it to either the interested scientist who wants a more in depth discussion, or an interested non-scientist who would need a lot of prior knowledge from other sources if they are really going to gain from this book.If you are interested in learning the background of the companies and major players in what is sure to be a new biotech industry, then this is the book for you. But if you want to understand the biology or technology or think about the considerable potential consequences then look elsewhere.
  • Rating: 3 out of 5 stars
    3/5
    Very interesting topic, disappointing book. Davies' focuses more on the commercial implications for genetics and the companies and leaders in the field, rather than explaining what's happening to amateurs interested in the field. One can't help but being impressed by the speed of development in this area of science.
  • Rating: 4 out of 5 stars
    4/5
    A whirlwind tour of the state of the art in genomic technology circa 2010 by a well informed and well connected author. I found the book well written and a valuable source of information on and insight into a rapidly changing field. There is information in this book which is difficult to find anywhere else. What is the technology used by Halcycon Molecular? What is the origin of the technology in use at Ion Torrent? What were insiders saying at critical time points about the various technologies?Not for amateurs? Perhaps. For those with more than a passing interest in developments in personal genomics, however, it is a must read.